Comparison of the free radical scavenging activity of captopril versus enalapril: a three month in vivo study in hypertensive diabetic patients.

SC Bain, CA Le Guen, J Lunec… - Journal of human …, 1991 - europepmc.org
Lipid peroxides and fluorescent serum proteins, possible markers of free radical activity, are
increased in diabetic patients, particularly those with angiopathy. Captopril, an angiotensin
converting enzyme (ACE) inhibitor, scavenges free radicals in vitro independently of ACE
inhibition. This is probably due to the presence of a sulphydryl group which is not present in
other ACE inhibitor drugs. We have compared the effects of captopril and enalapril on free
radical activity in thirty-two diabetic subjects with hypertension (BP greater than 160/95 …
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[引用][C] Comparison of the free radical scavenging activity of captopril versus enalapril: a 3-month in vivo study in hypertensive diabetic patients

B SC - J Hum Hypertens, 1991 - cir.nii.ac.jp
Comparison of the free radical scavenging activity of captopril versus enalapril : a 3-month
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